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1 keywords

CATH Domain 3n7kB01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.120 Jelly Rolls
Homologous Superfamily 2.60.120.200  

Domain Context

CATH Clusters

Superfamily 2.60.120.200
Functional Family Botulinum neurotoxin type A

Enzyme Information

3.4.24.69
Bontoxilysin.
based on mapping to UniProt P18640
Limited hydrolysis of proteins of the neuroexocytosis apparatus, synaptobrevins, SNAP25 or syntaxin. No detected action on small molecule substrates.
-!- Belongs to peptidase family M27.

UniProtKB Entries (1)

P18640
BXC_CBCP
Clostridium phage c-st
Botulinum neurotoxin type C

PDB Structure

PDB 3N7K
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Identification of a Unique Ganglioside Binding Loop within Botulinum Neurotoxins C and D-SA .
Karalewitz, A.P., Kroken, A.R., Fu, Z., Baldwin, M.R., Kim, J.J., Barbieri, J.T.
Biochemistry
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