CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.590 | Creatine Kinase; Chain A, domain 2 |
|
3.30.590.20 |
Domain Context
CATH Clusters
| Superfamily | 3.30.590.20 |
| Functional Family |
Enzyme Information
| 6.3.2.3 |
Glutathione synthase.
based on mapping to UniProt Q8DXM9
ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione.
|
| 6.3.2.2 |
Glutamate--cysteine ligase.
based on mapping to UniProt Q8DXM9
ATP + L-glutamate + L-cysteine = ADP + phosphate + gamma-L-glutamyl-L- cysteine.
-!- Can use L-aminohexanoate in place of glutamate.
|
UniProtKB Entries (1)
| Q8DXM9 |
GSHAB_STRA5
Streptococcus agalactiae 2603V/R
Glutathione biosynthesis bifunctional protein GshAB
|
PDB Structure
| PDB | 3LN6 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structures of two bifunctional gamma-Glutamate-cysteine Ligase/Glutathione synthetases (GshF) reveal a novel hybrid ATP-grasp fold
To be Published
|