CATH Classification

Domain Context

CATH Clusters

Superfamily Mur-like, catalytic domain
Functional Family

Enzyme Information

6.3.2.9
UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase.
based on mapping to UniProt Q8E186
ATP + UDP-N-acetyl-alpha-D-muramoyl-L-alanine + D-glutamate = ADP + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate.
-!- Involved in the synthesis of a cell-wall peptide in bacteria.

UniProtKB Entries (1)

Q8E186
MURD_STRA5
Streptococcus agalactiae 2603V/R
UDP-N-acetylmuramoylalanine--D-glutamate ligase

PDB Structure

PDB 3LK7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Crystal Structure of UDP-N-acetylmuramoylalanine-D-glutamate (MurD) ligase from Streptococcus agalactiae to 1.5A
Stein, A.J., Sather, A., Shakelford, G., Joachimiak, A.
To be Published