CATH Domain 3kudA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	KRAS proto-oncogene, GTPase

Enzyme Information

UniProtKB Entries (1)

RAF1_HUMAN

Homo sapiens

RAF proto-oncogene serine/threonine-protein kinase

PDB Structure

PDB	3KUD
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	What makes Ras an efficient molecular switch: a computational, biophysical, and structural study of Ras-GDP interactions with mutants of Raf. Filchtinski, D., Sharabi, O., Ruppel, A., Vetter, I.R., Herrmann, C., Shifman, J.M. J.Mol.Biol.