CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family tryptophan--tRNA ligase, cytoplasmic

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt Q12109
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

Q12109
SYWC_YEAST
Saccharomyces cerevisiae S288C
Tryptophan--tRNA ligase, cytoplasmic

PDB Structure

PDB 3KT6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of Saccharomyces cerevisiae tryptophanyl-tRNA synthetase: new insights into the mechanism of tryptophan activation and implications for anti-fungal drug design
Zhou, M., Dong, X., Shen, N., Zhong, C., Ding, J.
Nucleic Acids Res.