CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.572 | Thymidylate Synthase; Chain A |
|
3.30.572.10 | Thymidylate synthase/dCMP hydroxymethylase domain |
Domain Context
CATH Clusters
| Superfamily | Thymidylate synthase/dCMP hydroxymethylase domain |
| Functional Family |
Enzyme Information
UniProtKB Entries (1)
| Q8T5T8 |
Q8T5T8_TRYCR
Trypanosoma cruzi
Bifunctional dihydrofolate reductase-thymidylate synthase
|
PDB Structure
| PDB | 3KJS |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Synthesis and characterization of potent inhibitors of Trypanosoma cruzi dihydrofolate reductase.
Bioorg.Med.Chem.
|