|3.90.70||Cathepsin B; Chain A|
|Functional Family||Cathepsin B|
based on mapping to UniProt P07858
Hydrolysis of proteins with broad specificity for peptide bonds. Preferentially cleaves -Arg-Arg-|-Xaa bonds in small molecule substrates (thus differing from cathepsin L). In addition to being an endopeptidase, shows peptidyl-dipeptidase activity, liberating C-terminal dipeptides.
UniProtKB Entries (1)
Stefin A displaces the occluding loop of cathepsin B only by as much as required to bind to the active site cleft