CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1160 | Carbamate kinase |
|
3.40.1160.10 | Acetylglutamate kinase-like |
Domain Context
CATH Clusters
| Superfamily | Acetylglutamate kinase-like |
| Functional Family |
Enzyme Information
| 2.7.4.26 |
Isopentenyl phosphate kinase.
based on mapping to UniProt Q60352
ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate.
-!- The enzyme is involved in the mevalonate pathway in Archaea. -!- The activity has also been identified in the plant Mentha piperita (peppermint). -!- It is strictly specific for ATP but can use other phosphate acceptors such as dimethylallyl phosphate, geranyl phosphate, or fosfomycin.
|
UniProtKB Entries (1)
| Q60352 |
IPK_METJA
Methanocaldococcus jannaschii DSM 2661
Isopentenyl phosphate kinase
|
PDB Structure
| PDB | 3K52 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Mutation of archaeal isopentenyl phosphate kinase highlights mechanism and guides phosphorylation of additional isoprenoid monophosphates.
Acs Chem.Biol.
|
