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CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family Tryptophan--tRNA ligase

Enzyme Information

6.1.1.2
Tryptophan--tRNA ligase.
based on mapping to UniProt O59584
ATP + L-tryptophan + tRNA(Trp) = AMP + diphosphate + L-tryptophyl- tRNA(Trp).

UniProtKB Entries (1)

O59584
SYW_PYRHO
Pyrococcus horikoshii OT3
Tryptophan--tRNA ligase

PDB Structure

PDB 3JXE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of P. horikoshii tryptophanyl-tRNA synthetase and structure-based phylogenetic analysis suggest an archaeal origin of tryptophanyl-tRNA synthetase
Zhou, M., Dong, X., Zhong, C., Shen, N., Yang, B., Ding, J.
To be Published
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