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1 keywords

CATH Domain 3jwpA02

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.1600 SIR2/SIRT2 'Small Domain'
Homologous Superfamily 3.30.1600.10 SIR2/SIRT2 'Small Domain'

Domain Context

CATH Clusters

Superfamily SIR2/SIRT2 'Small Domain'
Functional Family

Enzyme Information

3.5.1.-
In linear amides.
based on mapping to UniProt Q8IE47

UniProtKB Entries (1)

Q8IE47
SIR5_PLAF7
Plasmodium falciparum 3D7
NAD-dependent protein deacylase Sir2A

PDB Structure

PDB 3JWP
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of Plasmodium falciparum SIR2A (PF13_0152) in complex with AMP
Wernimont, A.K., Hutchinson, A., Lin, Y.H., MacKenzie, F., Senisterra, G., Allali-Hassanali, A., Vedadi, M., Ravichandran, M., Cossar, D., Kozieradzki, I., Zhao, Y., Schapira, M., Arrowsmith, C.H., Bountra, C., Weigelt, J., Edwards, A.M., Hui, R., Qiu, W., Brand, V.
TO BE PUBLISHED
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