CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.1100
Functional Family Cysteine synthase

Enzyme Information

2.5.1.47
Cysteine synthase.
based on mapping to UniProt P45040
O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate.
-!- Some alkyl thiols, cyanide, pyrazole and some other heterocyclic compounds can act as acceptors. -!- Not identical with EC 2.5.1.51, EC 2.5.1.52 and EC 2.5.1.53. -!- Formerly EC 4.2.99.8.

UniProtKB Entries (1)

P45040
CYSK_HAEIN
Haemophilus influenzae Rd KW20
Cysteine synthase

PDB Structure

PDB 3IQI
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design of o-acetylserine sulfhydrylase inhibitors by mimicking nature.
Salsi, E., Bayden, A.S., Spyrakis, F., Amadasi, A., Campanini, B., Bettati, S., Dodatko, T., Cozzini, P., Kellogg, G.E., Cook, P.F., Roderick, S.L., Mozzarelli, A.
J.Med.Chem.