CATH Domain 3ikeB00

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.1330	60s Ribosomal Protein L30; Chain: A;
	3.30.1330.50	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

Superfamily	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Functional Family	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

4.6.1.12

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase.

based on mapping to UniProt Q63T71

2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl- D-erythritol 2,4-cyclodiphosphate + CMP.

-!- Forms part of an alternative nonmevalonate pathway for terpenoid biosynthesis.

ISPF_BURPS

Burkholderia pseudomallei K96243

2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

PDB	3IKE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. Begley, D.W., Hartley, R.C., Davies, D.R., Edwards, T.E., Leonard, J.T., Abendroth, J., Burris, C.A., Bhandari, J., Myler, P.J., Staker, B.L., Stewart, L.J. J Struct Funct Genomics