CATH Classification

Domain Context

CATH Clusters

Superfamily Endonuclease/exonuclease/phosphatase
Functional Family

Enzyme Information

3.1.4.3
Phospholipase C.
based on mapping to UniProt P09978
A phosphatidylcholine + H(2)O = 1,2-diacyl-sn-glycerol + phosphocholine.
-!- The bacterial enzyme also acts on sphingomyelin and phosphatidylinositol. -!- The enzyme from seminal plasma does not act on phosphatidylinositol.

UniProtKB Entries (1)

P09978
PHLC_STAAU
Staphylococcus aureus
Phospholipase C

PDB Structure

PDB 3I5V
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and biological functions of beta toxin from Staphylococcus aureus: Role of the hydrophobic beta hairpin in virulence
Huseby, M., Shi, K., Kruse, A.C., Digre, J., Mengistu, F., Bohach, G.A., Schlievert, P.S., Ohlendorf, D.H., Earhart, C.A.
To be Published