CATH Classification

Domain Context

CATH Clusters

Superfamily Jelly Rolls
Functional Family

Enzyme Information

5.3.3.19
3-((4R)-4-hydroxycyclohexa-1,5-dien-1-yl)-2-oxopropanoate isomerase.
based on mapping to UniProt P39639
3-((4R)-4-hydroxycyclohexa-1,5-dien-1-yl)-2-oxopropanoate = 3-((1E,4R)-4- hydroxycyclohex-2-en-1-ylidene)-2-oxopropanoate.
-!- The enzyme, characterized from the bacterium Bacillus subtilis, is involved in the biosynthesis of the nonribosomally synthesized dipeptide antibiotic bacilysin, composed of L-alanine and L-anticapsin. -!- The enzyme can interconvert the (E) isomer formed in the reaction into the (Z) isomer, although this isomerization is not part of the pathway leading to bacilysin.

UniProtKB Entries (1)

P39639
BACB_BACSU
Bacillus subtilis subsp. subtilis str. 168
H2HPP isomerase

PDB Structure

PDB 3H9A
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Analysis of multiple crystal forms of Bacillus subtilis BacB suggests a role for a metal ion as a nucleant for crystallization
Rajavel, M., Gopal, B.
Acta Crystallogr.,Sect.D