CATH Classification

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family

Enzyme Information

2.1.1.316
Mitomycin 6-O-methyltransferase.
based on mapping to UniProt Q9X5T6
(1) S-adenosyl-L-methionine + 6-demethylmitomycin A = S-adenosyl-L- homocysteine + mitomycin A. (2) S-adenosyl-L-methionine + 6-demethylmitomycin B = S-adenosyl-L- homocysteine + mitomycin B.
-!- The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B.

UniProtKB Entries (1)

Q9X5T6
MMCR_STRLA
Streptomyces lavendulae
Mitomycin biosynthesis 6-O-methyltransferase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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