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1 keywords

CATH Domain 3groB00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.1820 alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily alpha/beta hydrolase
Functional Family palmitoyl-protein thioesterase 1

Enzyme Information

3.1.2.22
Palmitoyl-protein hydrolase.
based on mapping to UniProt P50897
Palmitoyl-[protein] + H(2)O = palmitate + [protein].
-!- Specific for long-chain thioesters of fatty acids. -!- Hydrolyzes fatty acids from S-acylated cysteine residues in proteins, palmitoyl cysteine and palmitoyl-CoA.

UniProtKB Entries (1)

P50897
PPT1_HUMAN
Homo sapiens
Palmitoyl-protein thioesterase 1

PDB Structure

PDB 3GRO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Human palmitoyl-protein thioesterase 1
Dobrovetsky, E., Seitova, A., Tong, Y., Tempel, W., Dong, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Cossar, D., Park, H.
To be Published
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