CATH Domain 3gbsA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	Cutinase 1

Enzyme Information

3.1.1.74

Cutinase.

based on mapping to UniProt P52956

Cutin + H(2)O = cutin monomers.

-!- Cutin, a polymeric structural component of plant cuticles, is an hydroxy fatty acid polymer, usually C(16) or C(18) and that contains one to three hydroxyl groups. -!- The enzyme from several fungal sources also hydrolyzes the p-nitrophenyl esters of hexadecanoic acid. -!- It is however inactive toward several esters that are substrates for non-specific esterases.

UniProtKB Entries (1)

P52956

CUTI1_ASPOR

Aspergillus oryzae RIB40

Cutinase 1

PDB Structure

PDB	3GBS
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural and functional studies of Aspergillus oryzae cutinase: enhanced thermostability and hydrolytic activity of synthetic ester and polyester degradation. Liu, Z., Gosser, Y., Baker, P.J., Ravee, Y., Lu, Z., Alemu, G., Li, H., Butterfoss, G.L., Kong, X.P., Gross, R., Montclare, J.K. J.Am.Chem.Soc.