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1 keywords

CATH Domain 3g8hA00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.90 Phospholipase A2
Homologous Superfamily 1.20.90.10 Phospholipase A2 domain

Domain Context

CATH Clusters

Superfamily Phospholipase A2 domain
Functional Family Basic phospholipase A2 homolog

Enzyme Information

3.1.1.4
Phospholipase A(2).
based on mapping to UniProt P11407
Phosphatidylcholine + H(2)O = 1-acylglycerophosphocholine + a carboxylate.
-!- Also acts on phosphatidylethanolamine, choline plasmalogen and phosphatides, removing the fatty acid attached to the 2-position.

UniProtKB Entries (1)

P11407
PA2BC_VIPAA
Vipera ammodytes ammodytes
Basic phospholipase A2 ammodytoxin C

PDB Structure

PDB 3G8H
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Comparative structural studies of two natural isoforms of ammodytoxin, phospholipases A2 from Vipera ammodytes ammodytes which differ in neurotoxicity and anticoagulant activity
Saul, F.A., Prijatelj-Znidarsic, P., Vulliez-le Normand, B., Villette, B., Raynal, B., Pungercar, J., Krizaj, I., Faure, G.
J.Struct.Biol.
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