CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.3200 | Hypothetical protein af0941 |
|
1.10.3200.20 | DNA Polymerase alpha, zinc finger |
Domain Context
CATH Clusters
| Superfamily | DNA Polymerase alpha, zinc finger |
| Functional Family | DNA polymerase |
Enzyme Information
| 2.7.7.7 |
DNA-directed DNA polymerase.
based on mapping to UniProt P13382
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
-!- Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time. -!- Cannot initiate a chain de novo. -!- Requires a primer which may be DNA or RNA. -!- See also EC 2.7.7.49.
|
UniProtKB Entries (1)
| P38121 |
DPOA2_YEAST
Saccharomyces cerevisiae S288C
DNA polymerase alpha subunit B
|
PDB Structure
| PDB | 3FLO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
3D architecture of DNA Pol alpha reveals the functional core of multi-subunit replicative polymerases
Embo J.
|
