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1 keywords

CATH Domain 3fkbD00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.70 Alpha-Beta Plaits
Homologous Superfamily 3.30.70.141 Nucleoside diphosphate kinase-like domain

Domain Context

CATH Clusters

Superfamily Nucleoside diphosphate kinase-like domain
Functional Family Nucleoside diphosphate kinase

Enzyme Information

2.7.4.6
Nucleoside-diphosphate kinase.
based on mapping to UniProt P22887
ATP + nucleoside diphosphate = ADP + nucleoside triphosphate.
-!- Many nucleoside diphosphates can act as acceptors. -!- Many ribo- and deoxyribonucleoside triphosphates can act as donors.

UniProtKB Entries (1)

P22887
NDKC_DICDI
Dictyostelium discoideum
Nucleoside diphosphate kinase, cytosolic

PDB Structure

PDB 3FKB
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Nucleoside diphosphate kinase and the activation of antiviral phosphonate analogs of nucleotides: binding mode and phosphorylation of tenofovir derivatives
Koch, K., Chen, Y.X., Feng, J.Y., Borroto-Esoda, K., Deville-Bonne, D., Gallois-Montbrun, S., Janin, J., Morera, S.
Nucleosides Nucleotides Nucleic Acids
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