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1 keywords

CATH Domain 3fc6D00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Oxysterols receptor LXR-alpha isoform 1

Enzyme Information

UniProtKB Entries (2)

P19793
RXRA_HUMAN
Homo sapiens
Retinoic acid receptor RXR-alpha
Q9Z0Y9
NR1H3_MOUSE
Mus musculus
Oxysterols receptor LXR-alpha

PDB Structure

PDB 3FC6
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Synthesis and SAR of potent LXR agonists containing an indole pharmacophore.
Washburn, D.G., Hoang, T.H., Campobasso, N., Smallwood, A., Parks, D.J., Webb, C.L., Frank, K.A., Nord, M., Duraiswami, C., Evans, C., Jaye, M., Thompson, S.K.
Bioorg.Med.Chem.Lett.
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