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1 keywords

CATH Domain 3f1oA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.30 2-Layer Sandwich
Topology 3.30.450 Beta-Lactamase
Homologous Superfamily 3.30.450.20 PAS domain

Domain Context

CATH Clusters

Superfamily PAS domain
Functional Family Hypoxia-inducible factor 1-alpha isoform 1

Enzyme Information

UniProtKB Entries (1)

Q99814
EPAS1_HUMAN
Homo sapiens
Endothelial PAS domain-containing protein 1

PDB Structure

PDB 3F1O
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.
Scheuermann, T.H., Tomchick, D.R., Machius, M., Guo, Y., Bruick, R.K., Gardner, K.H.
Proc.Natl.Acad.Sci.USA
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