CATH Classification
Level | CATH Code | Description |
---|---|---|
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4 | Few Secondary Structures |
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4.10 | Irregular |
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4.10.140 | Epsilon-Thrombin; Chain L |
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4.10.140.10 | Thrombin light chain domain |
Domain Context
CATH Clusters
Superfamily | Thrombin light chain domain |
Functional Family |
Enzyme Information
3.4.21.5 |
Thrombin.
based on mapping to UniProt P19221
Selective cleavage of Arg-|-Gly bonds in fibrinogen to form fibrin and release fibrinopeptides A and B.
-!- More selective than trypsin and plasmin. -!- Belongs to peptidase family S1. -!- Formerly EC 3.4.4.13.
|
UniProtKB Entries (1)
P19221 |
THRB_MOUSE
Mus musculus
Prothrombin
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PDB Structure
PDB | 3EDX |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Molecular Basis for the Kinetic Differences of the W215A/E217A Mutant of Human and Murine Thrombin
To be Published
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