CATH Classification

Domain Context

CATH Clusters

Superfamily 1.50.10.10
Functional Family LanC-like protein 1

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt O43813
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

O43813
LANC1_HUMAN
Homo sapiens
Glutathione S-transferase LANCL1

PDB Structure

PDB 3E73
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of human lanthionine synthetase C-like protein 1 and its interaction with Eps8 and glutathione
Zhang, W., Wang, L., Liu, Y., Xu, J., Zhu, G., Cang, H., Li, X., Bartlam, M., Hensley, K., Li, G., Rao, Z., Zhang, X.C.
Genes Dev.