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CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family MTA/SAH nucleosidase family protein

Enzyme Information

3.2.2.9
Adenosylhomocysteine nucleosidase.
based on mapping to UniProt Q9KPI8
S-adenosyl-L-homocysteine + H(2)O = S-(5-deoxy-D-ribos-5-yl)-L- homocysteine + adenine.

UniProtKB Entries (1)

Q9KPI8
MTNN_VIBCH
Vibrio cholerae O1 biovar El Tor str. N16961
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase

PDB Structure

PDB 3DP9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Transition state analogs of 5'-methylthioadenosine nucleosidase disrupt quorum sensing.
Gutierrez, J.A., Crowder, T., Rinaldo-Matthis, A., Ho, M.C., Almo, S.C., Schramm, V.L.
Nat.Chem.Biol.
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