CATH Domain 3dp2E00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.129	Thiol Ester Dehydrase; Chain A
	3.10.129.10	Hotdog Thioesterase

Domain Context

CATH Clusters

Superfamily	Hotdog Thioesterase
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q5G940_HELPX

Helicobacter pylori

3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ

PDB Structure

PDB	3DP2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Discovering potent inhibitors against the beta-hydroxyacyl-acyl carrier protein dehydratase (FabZ) of Helicobacter pylori: structure-based design, synthesis, bioassay, and crystal structure determination. He, L., Zhang, L., Liu, X., Li, X., Zheng, M., Li, H., Yu, K., Chen, K., Shen, X., Jiang, H., Liu, H. J.Med.Chem.