CATH Domain 3dolB04

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.270	Reverse transcriptase/Diguanylate cyclase domain

Domain Context

CATH Clusters

Superfamily	3.30.70.270
Functional Family	Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

A7YKL0_9HIV1

Human immunodeficiency virus 1

Pol protein

PDB Structure

PDB	3DOL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural basis for the improved drug resistance profile of new generation benzophenone non-nucleoside HIV-1 reverse transcriptase inhibitors. Ren, J., Chamberlain, P.P., Stamp, A., Short, S.A., Weaver, K.L., Romines, K.R., Hazen, R., Freeman, A., Ferris, R.G., Andrews, C.W., Boone, L., Chan, J.H., Stammers, D.K. J.Med.Chem.