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1 keywords

CATH Domain 3daqA00

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.20 Alpha-Beta Barrel
Topology 3.20.20 TIM Barrel
Homologous Superfamily 3.20.20.70 Aldolase class I

Domain Context

CATH Clusters

Superfamily Aldolase class I
Functional Family

Enzyme Information

4.3.3.7
4-hydroxy-tetrahydrodipicolinate synthase.
based on mapping to UniProt Q6GH13
Pyruvate + L-aspartate-4-semialdehyde = (4S)-4-hydroxy-2,3,4,5- tetrahydro-(2S)-dipicolinate + H(2)O.
-!- Formerly EC 4.2.1.52.

UniProtKB Entries (1)

Q6GH13
DAPA_STAAR
Staphylococcus aureus subsp. aureus MRSA252
4-hydroxy-tetrahydrodipicolinate synthase

PDB Structure

PDB 3DAQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure and evolution of a novel dimeric enzyme from a clinically-important bacterial pathogen.
Burgess, B.R., Dobson, R.C.J., Bailey, M.F., Atkinson, S.C., Griffin, M.D.W., Jameson, G.B., Parker, M.W., Gerrard, J.A., Perugini, M.A.
J.Biol.Chem.
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