CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.50.360
Functional Family NAD(P)H dehydrogenase (quinone)

Enzyme Information

1.6.5.2
NAD(P)H dehydrogenase (quinone).
based on mapping to UniProt P0A8G6
NAD(P)H + a quinone = NAD(P)(+) + a hydroquinone.
-!- The enzyme catalyzes a two-electron reduction and has a preference for short-chain acceptor quinones, such as ubiquinone, benzoquinone, juglone and duroquinone. -!- The animal, but not the plant, form of the enzyme is inhibited by dicoumarol. -!- Formerly EC 1.6.99.2.

UniProtKB Entries (1)

P0A8G6
NQOR_ECOLI
Escherichia coli K-12
NAD(P)H dehydrogenase (quinone)

PDB Structure

PDB 3B6M
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of the NADH:quinone oxidoreductase WrbA from Escherichia coli.
Andrade, S.L., Patridge, E.V., Ferry, J.G., Einsle, O.
J.Bacteriol.