CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Guanine nucleotide-binding protein G(q) subunit alpha

Enzyme Information

UniProtKB Entries (3)

P21279
GNAQ_MOUSE
Mus musculus
Guanine nucleotide-binding protein G(q) subunit alpha
P10824
GNAI1_RAT
Rattus norvegicus
Guanine nucleotide-binding protein G(i) subunit alpha-1
P63212
GBG2_BOVIN
Bos taurus
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

PDB Structure

PDB 3AH8
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the specific inhibition of heterotrimeric Gq protein by a small molecule.
Nishimura, A., Kitano, K., Takasaki, J., Taniguchi, M., Mizuno, N., Tago, K., Hakoshima, T., Itoh, H.
Proc.Natl.Acad.Sci.USA