CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Guanine nucleotide-binding protein subunit alpha-13 |
Enzyme Information
UniProtKB Entries (2)
| Q92888 |
ARHG1_HUMAN
Homo sapiens
Rho guanine nucleotide exchange factor 1
|
| P27601 |
GNA13_MOUSE
Mus musculus
Guanine nucleotide-binding protein subunit alpha-13
|
PDB Structure
| PDB | 3AB3 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Identification of critical residues in G(alpha)13 for stimulation of p115RhoGEF activity and the structure of the G(alpha)13-p115RhoGEF regulator of G protein signaling homology (RH) domain complex.
J.Biol.Chem.
|
