CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.920 | Histone Acetyltransferase; Chain A |
|
1.20.920.10 | Bromodomain-like |
Domain Context
CATH Clusters
| Superfamily | Bromodomain-like |
| Functional Family | Transcription initiation factor TFIID subunit |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P21675
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
| 2.3.1.48 |
Histone acetyltransferase.
based on mapping to UniProt P21675
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
|
UniProtKB Entries (1)
| Q9Y294 |
ASF1A_HUMAN
Homo sapiens
Histone chaperone ASF1A
|
PDB Structure
| PDB | 3AAD |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of the histone chaperone CIA/ASF1-double bromodomain complex linking histone modifications and site-specific histone eviction
Proc.Natl.Acad.Sci.USA
|
