CATH Domain 3a74A02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.930	BirA Bifunctional Protein; domain 2
	3.30.930.10	Bira Bifunctional Protein; Domain 2

Domain Context

CATH Clusters

Superfamily	Bira Bifunctional Protein; Domain 2
Functional Family	Lysine--tRNA ligase

Enzyme Information

6.1.1.6

Lysine--tRNA ligase.

based on mapping to UniProt Q9RHV9

ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys).

UniProtKB Entries (1)

SYK_GEOSE

Geobacillus stearothermophilus

Lysine--tRNA ligase

PDB Structure

PDB	3A74
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal Structure of Lysyl-tRNA Synthetase from Bacillus stearothermophilus in Complex with Diadenosine Tetraphosphate (AP4A): Insights into AP4A Synthesis Mechanisms and Implication for Recognition of Discriminator Base of tRNA^Lys Sakurama, H., Takita, T., Mikami, B., Itoh, T., Yasukawa, K., Inouye, K. To be Published