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CATH Classification

Domain Context

CATH Clusters

Superfamily 6.10.140.720
Functional Family

Enzyme Information

2.7.7.48
RNA-directed RNA polymerase.
based on mapping to UniProt P03431
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
-!- Catalyzes RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time. -!- Can initiate a chain de novo. -!- See also EC 2.7.7.6.

UniProtKB Entries (1)

P03428
PB2_I34A1
Influenza A virus (A/Puerto Rico/8/1934(H1N1))
Polymerase basic protein 2

PDB Structure

PDB 2ZTT
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase
Sugiyama, K., Obayashi, E., Kawaguchi, A., Suzuki, Y., Tame, J.R.H., Nagata, K., Park, S.-Y.
Embo J.
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