CATH Classification

Domain Context

CATH Clusters

Superfamily Zn peptidases
Functional Family Glutaminyl-peptide cyclotransferase

Enzyme Information

2.3.2.5
Glutaminyl-peptide cyclotransferase.
based on mapping to UniProt Q16769
L-glutaminyl-peptide = 5-oxoprolyl-peptide + NH(3).
-!- Involved in the formation of thyrotropin-releasing hormone and other biologically active peptides containing N-terminal pyroglutamyl residues. -!- The enzyme from papaya also acts on glutaminyl-tRNA.

UniProtKB Entries (1)

Q16769
QPCT_HUMAN
Homo sapiens
Glutaminyl-peptide cyclotransferase

PDB Structure

PDB
External Links
Method
Organism
Primary Citation
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