CATH Classification

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Kallikrein 1-related peptidase C9

Enzyme Information

3.4.21.77
Semenogelase.
based on mapping to UniProt P07288
Preferential cleavage: -Tyr-|-Xaa-.
-!- Slowly inhibited by alpha-1-antichymotrypsin. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P07288
KLK3_HUMAN
Homo sapiens
Prostate-specific antigen

PDB Structure

PDB 2ZCK
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a ternary complex between human prostate-specific antigen, its substrate acyl intermediate and an activating antibody
Michel, S., Muller, B.H., Bossus, M., Ducancel, F., Jolivet-Reynaud, C., Stura, E.A.
J.Mol.Biol.