CATH Domain 2zbfA04
|3.40.1110||Calcium-transporting ATPase, cytoplasmic domain N|
|3.40.1110.10||Calcium-transporting ATPase, cytoplasmic domain N|
|Superfamily||Calcium-transporting ATPase, cytoplasmic domain N|
|Functional Family||Calcium-transporting ATPase|
P-type Ca(2+) transporter.
based on mapping to UniProt P04191
ATP + H(2)O + Ca(2+)(Side 1) = ADP + phosphate + Ca(2+)(Side 2).
-!- A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. -!- This enzyme family comprises three types of Ca(2+)-transporting enzymes that are found in the plasma membrane, the sarcoplasmic reticulum, in yeast, and in some bacteria. -!- The enzymes from plasma membrane and from yeast have been shown to transport one ion per ATP hydrolyzed whereas those from the sarcoplasmic reticulum transport two ions per ATP hydrolyzed. -!- In muscle cells Ca(2+) is transported from the cytosol into the sarcoplasmic reticulum. -!- Formerly EC 22.214.171.124 and EC 126.96.36.199.
UniProtKB Entries (1)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump