CATH Domain 2yh0A02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	U2 snRNP auxiliary factor large subunit

Enzyme Information

UniProtKB Entries (1)

U2AF2_HUMAN

Homo sapiens

Splicing factor U2AF 65 kDa subunit

PDB Structure

PDB	2YH0
External Links	PDBSum Proteopedia
Method	SOLUTION NMR
Organism
Primary Citation	Multi-Domain Conformational Selection Underlies Pre-Mrna Splicing Regulation by U2Af Mackereth, C.D., Madl, T., Bonnal, S., Simon, B., Zanier, K., Gasch, A., Rybin, V., Valcarcel, J., Sattler, M. Nature