CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 | |
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
Superfamily | 3.40.47.10 |
Functional Family |
Enzyme Information
2.3.3.10 |
Hydroxymethylglutaryl-CoA synthase.
based on mapping to UniProt P54868
Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
-!- Formerly EC 4.1.3.5.
|
UniProtKB Entries (1)
P54868 |
HMCS2_HUMAN
Homo sapiens
Hydroxymethylglutaryl-CoA synthase, mitochondrial
|
PDB Structure
PDB | 2WYA |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal Structures of Human Hmg-Coa Synthase Isoforms Provide Insights Into Inherited Ketogenesis Disorders and Inhibitor Design.
J.Mol.Biol.
|