CATH Domain 2welA03

CATH Classification

Level	CATH Code	Description
	6	Special
	6.10	Helix non-globular
	6.10.140	Helix Hairpins
	6.10.140.620

Domain Context

CATH Clusters

Superfamily	6.10.140.620
Functional Family

Enzyme Information

2.7.11.17

Calcium/calmodulin-dependent protein kinase.

based on mapping to UniProt Q13557

ATP + a protein = ADP + a phosphoprotein.

-!- Requires calmodulin. -!- A wide range of proteins can act as acceptor, including vimentin, synapsin, glycogen synthase, myosin light-chains and the microtubule- associated tau protein. -!- Not identical with EC 2.7.11.18 or EC 2.7.11.26. -!- Formerly EC 2.7.1.120 and EC 2.7.1.123.

UniProtKB Entries (1)

Q13557

KCC2D_HUMAN

Homo sapiens

Calcium/calmodulin-dependent protein kinase type II subunit delta

PDB Structure

PDB	2WEL
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of the Camkiidelta/Calmodulin Complex Reveals the Molecular Mechanism of Camkii Kinase Activation. Rellos, P., Pike, A.C.W., Niesen, F.H., Salah, E., Lee, W.H., von Delft, F., Knapp, S. Plos Biol.

Network disruptions