CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.60 | 4-Layer Sandwich |
|
3.60.130 | Double-stranded beta-helix |
|
3.60.130.10 | Clavaminate synthase-like |
Domain Context
CATH Clusters
| Superfamily | Clavaminate synthase-like |
| Functional Family | Alpha-ketoglutarate-dependent L-arginine hydroxylase |
Enzyme Information
| 1.14.11.41 |
L-arginine hydroxylase.
based on mapping to UniProt Q6WZB0
L-arginine + 2-oxoglutarate + O(2) = (3S)-3-hydroxy-L-arginine + succinate + CO(2).
-!- The enzyme is involved in the biosynthesis of the cyclic pentapeptide antibiotic viomycin. -!- It differs from EC 1.14.20.7, because it does not form guanidine and (S)-1-pyrroline-5-carboxylate from 3-hydroxy-L-arginine.
|
UniProtKB Entries (1)
| Q6WZB0 |
ARGHX_STRVI
Streptomyces vinaceus
Alpha-ketoglutarate-dependent L-arginine hydroxylase
|
PDB Structure
| PDB | 2WBO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis for the Erythro-Stereospecificity of the L-Arginine Oxygenase Vioc in Viomycin Biosynthesis.
FEBS J.
|
