CATH Domain 2w2xB00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.300	P-loop containing nucleotide triphosphate hydrolases

Domain Context

CATH Clusters

Superfamily	P-loop containing nucleotide triphosphate hydrolases
Functional Family	Ras-related C3 botulinum toxin substrate 1

Enzyme Information

UniProtKB Entries (1)

PLCG2_HUMAN

Homo sapiens

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

PDB Structure

PDB	2W2X
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structural Insights Into Formation of an Active Signaling Complex between Rac and Phospholipase C Gamma 2. Bunney, T.D., Opaleye, O., Roe, S.M., Vatter, P., Baxendale, R.W., Walliser, C., Everett, K.L., Josephs, M.B., Christow, C., Rodrigues-Lima, F., Gierschik, P., Pearl, L.H., Katan, M. Mol.Cell