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1 keywords

CATH Domain 2v5eB00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.10 Ribbon
Topology 2.10.90 Cystine Knot Cytokines, subunit B
Homologous Superfamily 2.10.90.10 Cystine-knot cytokines

Domain Context

CATH Clusters

Superfamily Cystine-knot cytokines
Functional Family Glial cell line-derived neurotrophic factor

Enzyme Information

UniProtKB Entries (2)

P39905
GDNF_HUMAN
Homo sapiens
Glial cell line-derived neurotrophic factor
Q62997
GFRA1_RAT
Rattus norvegicus
GDNF family receptor alpha-1

PDB Structure

PDB 2V5E
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of the Glial Cell Line-Derived Neurotrophic Factor-Coreceptor Complex: Insights Into Ret Signaling and Heparin Binding.
Parkash, V., Leppanen, V.-M., Virtanen, H., Jurvansuu, J.-M., Bespalov, M.M., Sidorova, Y.A., Runeberg-Roos, P., Saarma, M., Goldman, A.
J.Biol.Chem.
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