CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family Estrogen sulfotransferase

Enzyme Information

2.8.2.2
Alcohol sulfotransferase.
based on mapping to UniProt Q6IMI6
3'-phosphoadenylyl sulfate + an alcohol = adenosine 3',5'-bisphosphate + an alkyl sulfate.
-!- Primary and secondary alcohols, including aliphatic alcohols, ascorbate, chloramphenicol, ephedrine and hydroxysteroids, but not phenolic steroids, can act as acceptors (cf. EC 2.8.2.15).

UniProtKB Entries (1)

Q6IMI6
ST1C3_HUMAN
Homo sapiens
Sulfotransferase 1C3

PDB Structure

PDB 2REO
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human sulfotransferase 1C3 (Sult1C3) in complex with PAP.
Pan, P., Tempel, W., Dong, A., Loppnau, P., Arrowsmith, C.H., Edwards, A.M., Sundstrom, M., Weigelt, J., Bochkarev, A., Plotnikov, A.N.
To be Published