CATH Domain 2r2oA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family

Enzyme Information

UniProtKB Entries (1)

PLXB1_HUMAN

Homo sapiens

Plexin-B1

PDB Structure

PDB	2R2O
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Binding of Rac1, Rnd1, and RhoD to a novel Rho GTPase interaction motif destabilizes dimerization of the plexin-B1 effector domain. Tong, Y., Chugha, P., Hota, P.K., Alviani, R.S., Li, M., Tempel, W., Shen, L., Park, H.W., Buck, M. J.Biol.Chem.