1 keywords

CATH Domain 2qe4A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Estrogen receptor

Enzyme Information

UniProtKB Entries (1)

P03372
ESR1_HUMAN
Homo sapiens
Estrogen receptor

PDB Structure

PDB 2QE4
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Benzopyrans as selective estrogen receptor beta agonists (SERBAs). Part 4: Functionalization of the benzopyran A-ring.
Norman, B.H., Richardson, T.I., Dodge, J.A., Pfeifer, L.A., Durst, G.L., Wang, Y., Durbin, J.D., Krishnan, V., Dinn, S.R., Liu, S., Reilly, J.E., Ryter, K.T.
Bioorg.Med.Chem.Lett.