CATH Domain 2pv7B02

×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.3660	6-phosphogluconate dehydrogenase C-terminal fold
	1.10.3660.10	6-phosphogluconate dehydrogenase C-terminal like domain

Domain Context

CATH Clusters

Superfamily	6-phosphogluconate dehydrogenase C-terminal like domain
Functional Family	T-protein

Enzyme Information

1.3.1.12	Prephenate dehydrogenase. based on mapping to UniProt P43902 Prephenate + NAD(+) = 4-hydroxyphenylpyruvate + CO(2) + NADH. -!- This enzyme in the enteric bacteria also possesses EC 5.4.99.5 activity and converts chorismate into prephenate.
5.4.99.5	Chorismate mutase. based on mapping to UniProt P43902 Chorismate = prephenate.

UniProtKB Entries (1)

TYRA_HAEIN

Haemophilus influenzae Rd KW20

T-protein

PDB Structure

PDB	2PV7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	The structure of Haemophilus influenzae prephenate dehydrogenase suggests unique features of bifunctional TyrA enzymes. Chiu, H.J., Abdubek, P., Astakhova, T., Axelrod, H.L., Carlton, D., Clayton, T., Das, D., Deller, M.C., Duan, L., Feuerhelm, J., Grant, J.C., Grzechnik, A., Han, G.W., Jaroszewski, L., Jin, K.K., Klock, H.E., Knuth, M.W., Kozbial, P., Krishna, S.S., Kumar, A., Marciano, D., McMullan, D., Miller, M.D., Morse, A.T., Nigoghossian, E., Okach, L., Reyes, R., Tien, H.J., Trame, C.B., van den Bedem, H., Weekes, D., Xu, Q., Hodgson, K.O., Wooley, J., Elsliger, M.A., Deacon, A.M., Godzik, A., Lesley, S.A., Wilson, I.A. Acta Crystallogr.,Sect.F