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1 keywords

CATH Domain 2psvA00

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.70 Cathepsin D, subunit A; domain 1
Homologous Superfamily 2.40.70.10 Acid Proteases

Domain Context

CATH Clusters

Superfamily Acid Proteases
Functional Family Gag-Pol polyprotein

Enzyme Information

UniProtKB Entries (1)

O38707
O38707_9HIV1
Human immunodeficiency virus 1
Protease

PDB Structure

PDB 2PSV
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Design of Mutation-resistant HIV Protease Inhibitors with the Substrate Envelope Hypothesis.
Chellappan, S., Kiran Kumar Reddy, G.S., Ali, A., Nalam, M.N., Anjum, S.G., Cao, H., Kairys, V., Fernandes, M.X., Altman, M.D., Tidor, B., Rana, T.M., Schiffer, C.A., Gilson, M.K.
Chem.Biol.Drug Des.
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