CATH Domain 2ps6B00

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CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.600	Farnesyl Diphosphate Synthase
	1.10.600.10	Farnesyl Diphosphate Synthase

Domain Context

CATH Clusters

Superfamily	Farnesyl Diphosphate Synthase
Functional Family

Enzyme Information

4.2.3.6

Trichodiene synthase.

based on mapping to UniProt P13513

(2E,6E)-farnesyl diphosphate = trichodiene + diphosphate.

-!- Formerly EC 4.1.99.6.

UniProtKB Entries (1)

TRI5_FUSSP

Fusarium sporotrichioides

Trichodiene synthase

PDB Structure

PDB	2PS6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism	Escherichia
Primary Citation	Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif. Vedula, L.S., Jiang, J., Zakharian, T., Cane, D.E., Christianson, D.W. Arch.Biochem.Biophys.