CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.40 | Beta Barrel |
|
2.40.50 | OB fold (Dihydrolipoamide Acetyltransferase, E2P) |
|
2.40.50.90 |
Domain Context
CATH Clusters
| Superfamily | 2.40.50.90 |
| Functional Family | Thermonuclease |
Enzyme Information
| 3.1.31.1 |
Micrococcal nuclease.
based on mapping to UniProt P00644
Endonucleolytic cleavage to nucleoside 3'-phosphates and 3'-phosphooligonucleotide end-products.
-!- Hydrolyzes double- or single-stranded substrate. -!- Similar enzymes: Chlamydomonas nuclease, spleen phosphodiesterase, spleen endonuclease. -!- Formerly EC 3.1.4.7.
|
UniProtKB Entries (1)
| P00644 |
NUC_STAAU
Staphylococcus aureus
Thermonuclease
|
PDB Structure
| PDB | 2PQE |
| External Links | |
| Method | SOLUTION NMR |
| Organism | Escherichia |
| Primary Citation |
Restricted backbone conformational and motional flexibilities of loops containing peptidyl-proline bonds dominate the enzyme activity of staphylococcal nuclease.
Biochemistry
|
